Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884202 | 0.86 | ESR1 (0.32) | TDP1 | |
| SCHEMBL2550095 | 0.85 | CA1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2543232 | 0.83 | HDAC3 (0.36) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2885908 | 0.79 | MEN1 (0.42) | TDP1KDM4ELMNANPSR1TSHR | |
| SCHEMBL2546914 | 0.79 | TSHR (0.34) | ALDH1A1ACHETDP1GAATSHR | |
| SCHEMBL2551352 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL2549712 | 0.77 | RIPK1 (0.33) | ALDH1A1ACHEKDM4ELMNA | |
| SCHEMBL2549515 | 0.77 | TSHR (0.38) | ALDH1A1ACHEMAPTLMNATSHR | |
| SCHEMBL2548298 | 0.76 | CYP3A4 (0.35) | ALDH1A1TDP1GAACYP3A4ALOX15 | |
| SCHEMBL2551359 | 0.76 | CA1 (0.52) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |