SCHEMBL3824691

SCHEMBL3824691

C=C(C)COc1ccccc1C1(OC)C=C[CH]C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
GPR174 Q9BXC1 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
POLB P06746 2/20 0.33
CCR8 P51685 1/20 0.32
KCNH2 Q12809 1/20 0.32
NPSR1 Q6W5P4 7/20 0.32
MEN1 O00255 6/20 0.32
KMT2A Q03164 6/20 0.32
MAPT P10636 6/20 0.32
TP53 P04637 5/20 0.32
MAPK1 P28482 5/20 0.32
ALDH1A1 P00352 4/20 0.32
HSD17B10 Q99714 4/20 0.32
USP2 O75604 3/20 0.32
ALOX12 P18054 3/20 0.32
GAA P10253 1/20 0.32
LMNA P02545 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29457182 0.73 SMN1; SMN2 (0.48) GPR174SMN1; SMN2POLBCCR8KCNH2
SCHEMBL9750660 0.73 SMN1; SMN2 (0.48) GPR174SMN1; SMN2POLBCCR8KCNH2
SCHEMBL5785927 0.70 SMN1; SMN2 (0.61) SMN1; SMN2POLBNPSR1MEN1KMT2A
SCHEMBL10870502 0.68 MEN1 (0.45) GPR174SMN1; SMN2POLBNPSR1MEN1
SCHEMBL5786743 0.67 NOTUM (0.51) SMN1; SMN2POLBNPSR1MEN1KMT2A
SCHEMBL8390273 0.67 GAA (0.55) GPR174SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL30947370 0.67 SIGMAR1 (0.62) TXNRD1TXNRD3TXNRD2GPR174SMN1; SMN2
SCHEMBL5784873 0.67 L3MBTL1 (0.61) GPR174SMN1; SMN2POLBNPSR1MEN1
SCHEMBL29384084 0.65 GRM4 (0.50) GPR174SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL2112699 0.65 GRM4 (0.50) GPR174SMN1; SMN2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090067046-A1 ANTIREFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
WO-2007001070-A1 ANTIREFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY FUJIFILM CORPORATION (JP) 2007-01-04 WO disclosed