Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | IDH2 | P48735 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3825503 | 0.87 | IDH2 (0.38) | BTKSLC1A3SLC1A2SLC1A1TUBB4A | |
| SCHEMBL3823848 | 0.81 | CYP2A6 (0.44) | BTKTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3824872 | 0.81 | BTK (0.38) | BTKSLC1A3SLC1A2SLC1A1TUBB4A | |
| SCHEMBL3830484 | 0.78 | TUBB4A (0.41) | BTKTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3827375 | 0.72 | TMIGD3 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3825362 | 0.70 | BCL9 (0.41) | BTKTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14003437 | 0.68 | CYP2A6 (0.44) | BTKTUBB4ATUBBTUBA3CTUBA1B | |
| Trifluoroacetic Acid SCHEMBL3830727 | 0.68 | SLC1A3 (0.33) | SLC1A3SLC1A2SLC1A1F2F3 | |
| SCHEMBL3830673 | 0.68 | CNR1 (0.41) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL3825505 | 0.68 | IDH2 (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |