Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055219 | 0.86 | TMIGD3 (0.53) | CNR1PTGDR2TMIGD3ADORA2AMAPT | |
| SCHEMBL3825362 | 0.83 | BCL9 (0.41) | TMIGD3ADORA2ASCN9ACHEK2MAPT | |
| SCHEMBL3823848 | 0.83 | CYP2A6 (0.44) | PTGDR2TMIGD3ADORA2ASCN9ACHEK2 | |
| SCHEMBL20573326 | 0.80 | PTGDR2 (0.44) | PTGDR2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL3827375 | 0.79 | TMIGD3 (0.43) | TMIGD3ADORA2ASCN9ACHEK2MAPT | |
| SCHEMBL20573401 | 0.79 | PTGDR2 (0.61) | PTGDR2ALDH1A1SLC6A9KDM4E | |
| SCHEMBL20573423 | 0.78 | PDE4D (0.51) | PTGDR2IKBKBSLC6A9KMT2AMEN1 | |
| SCHEMBL3830484 | 0.74 | TUBB4A (0.41) | TMIGD3ADORA2ACHEK2MAPTIKBKB | |
| SCHEMBL17796952 | 0.74 | CASP1 (0.43) | PTGDR2SCN9APPARGPPARA | |
| SCHEMBL20573238 | 0.73 | PTGDR2 (0.45) | CNR1PTGDR2SCN9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | claimed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | claimed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | claimed |