Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 4/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KYNU | Q16719 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357928 | 0.73 | TSHR (0.55) | SLC1A2SLC1A3SLC1A1HSD11B1LARS1 | |
| SCHEMBL6649064 | 0.72 | HSD11B1 (0.46) | HSD11B1ALDH1A1MAPTKDM4ECA12 | |
| SCHEMBL382491 | 0.71 | HSD11B1 (0.42) | SLC1A2SLC1A3SLC1A1HSD11B1LARS1 | |
| SCHEMBL28442855 | 0.70 | CA1 (0.48) | HSD11B1ALDH1A1CA12CA1CA2 | |
| SCHEMBL28797596 | 0.70 | MAPT (0.47) | HSD11B1ALDH1A1MAPTKDM4ECA12 | |
| SCHEMBL1464395 | 0.67 | HSD11B1 (0.48) | HSD11B1ALDH1A1CA12CA1CA2 | |
| SCHEMBL27853854 | 0.67 | KCNN4 (0.46) | HSD11B1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL10652867 | 0.67 | TSHR (0.48) | HSD11B1ALDH1A1MAPTKDM4ECA12 | |
| SCHEMBL4401812 | 0.66 | KIF11 (0.50) | ALDH1A1MAPTPTGS1KIF11CYP1A2 | |
| SCHEMBL10604801 | 0.66 | HSD11B1 (0.47) | HSD11B1ALDH1A1CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |