Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.60 |
| ▸ | CA2 | P00918 | 5/20 | 0.60 |
| ▸ | CA12 | O43570 | 4/20 | 0.60 |
| ▸ | CA7 | P43166 | 4/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.60 |
| ▸ | ESR1 | P03372 | 5/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627860 | 0.89 | CA1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL24036696 | 0.80 | TSHR (0.60) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5669277 | 0.79 | CA1 (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8486618 | 0.79 | CA1 (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27569922 | 0.78 | LMNA (0.55) | MEN1KMT2ALMNAMAPTPKM | |
| SCHEMBL6426303 | 0.78 | TDP1 (0.64) | CA2MEN1KMT2ALMNAMAPT | |
| SCHEMBL720782 | 0.77 | LMNA (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL247945 | 0.77 | CA1 (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28840271 | 0.75 | LMNA (0.61) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28762534 | 0.75 | LMNA (0.61) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089988-B1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-08-12 | — | — | EP | claimed |
| CN-1185259-C | Fluorophenyl resin compounds | AVENTIES PHARMACEUTICALS INC (US) | 2005-01-19 | — | — | CN | claimed |
| US-6639023-B1 | Such as 4-hydroxy, sulfonic acid or sulfonyl chloride-2,3,5,6-tetrafluorobenzamidomethyl-polystyrene resin; solid phase synthesis | AVENTIS PHARMACEUTICALS INC. | 2003-10-28 | — | — | US | claimed |
| CN-1306524-A | Fluorophenyl resin compounds | AVENTIES PHARMACEUTICALS INC (US) | 2001-08-01 | — | — | CN | claimed |
| CN-109996780-A | Polymerizable compound, polymerizable composition, polymerizable composition, macromolecule, optical film, optically anisotropic body, polarizing film, panel display apparatus, organic electroluminescence display device and method of manufacturing same, antireflection film and compound | 日本瑞翁株式会社 | 2019-07-09 | — | — | CN | disclosed |
| EP-2948456-A1 | BICYCLIC PYRIMIDONE COMPOUNDS AS INHIBITORS OF LP-PLA2 | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2015-12-02 | — | — | EP | disclosed |
| CN-102617580-B | Vasopressin v1a antagonists | VANTIA LTD | 2015-03-04 | — | — | CN | disclosed |
| WO-2014114249-A1 | BICYCLIC PYRIMIDONE COMPOUNDS AS INHIBITORS OF LP-PLA2 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2014-07-31 | — | — | WO | disclosed |
| EP-1089988-B1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1089988-A4 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2005-01-19 | — | — | EP | disclosed |
| CN-1185259-C | Fluorophenyl resin compounds | AVENTIES PHARMACEUTICALS INC (US) | 2005-01-19 | — | — | CN | disclosed |
| CN-1306524-A | Fluorophenyl resin compounds | AVENTIES PHARMACEUTICALS INC (US) | 2001-08-01 | — | — | CN | disclosed |
| EP-1089988-A1 | FLUOROPHENYL RESIN COMPOUNDS | Aventis Pharmaceuticals Products Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067228-A1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-12-29 | — | — | WO | disclosed |