Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263128 | 0.96 | SLC6A3 (0.59) | SLC6A3 | |
| SCHEMBL14660800 | 0.96 | SLC6A3 (0.59) | SLC6A3 | |
| SCHEMBL22263129 | 0.96 | SLC6A3 (0.59) | SLC6A3 | |
| SCHEMBL22263131 | 0.96 | SLC6A3 (0.59) | SLC6A3 | |
| SCHEMBL14671626 | 0.86 | — | — | |
| SCHEMBL5665179 | 0.85 | — | — | |
| SCHEMBL3889978 | 0.85 | SLC6A3 (0.47) | SLC6A3 | |
| SCHEMBL14671686 | 0.83 | — | — | |
| SCHEMBL15980940 | 0.82 | — | — | |
| SCHEMBL21009685 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776355-A4 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1776355-A2 | POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006028590-A1 | 1,1,2,2-TETRA (HETERO) ARYLETHANES OR 1,1,2-TRI (HETERO) ARYL-2-HETEROCYCLYLETHANES AS POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006014877-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |