⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263131 | 0.90 | SLC6A3 (0.59) | — | |
| SCHEMBL22263129 | 0.90 | SLC6A3 (0.59) | — | |
| SCHEMBL22263128 | 0.90 | SLC6A3 (0.59) | — | |
| SCHEMBL14660800 | 0.90 | SLC6A3 (0.59) | — | |
| SCHEMBL14671626 | 0.88 | — | — | |
| SCHEMBL15980940 | 0.86 | — | — | |
| SCHEMBL5665485 | 0.86 | KDM4E (0.46) | — | |
| SCHEMBL14671670 | 0.85 | — | — | |
| SCHEMBL3825525 | 0.85 | SLC6A3 (0.56) | — | |
| SCHEMBL14671686 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241082-A1 | Modulating vesicular monoamine transporter trafficking and function: a novel approach for the treatment of parkinson's disease | FLECKENSTEIN ANNETTE E | 2006-10-26 | — | — | US | disclosed |
| WO-2004026258-A2 | MODULATING VESICULAR MONOAMINE TRANSPORTER TRAFFICKING AND FUNCTION: A NOVEL APPROACH FOR THE TREATMENT OF PARKINSON’S DISEASE | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2004-04-01 | — | — | WO | disclosed |
| US-20030229122-A1 | Use of methylphenidate compounds to enhance memory | SENTION, INC. | 2003-12-11 | — | — | US | disclosed |
| EP-1315495-A2 | USE OF THREO-METHYLPHENIDATE COMPOUNDS TO ENHANCE MEMORY | Sention, Inc. (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20020132793-A1 | Use of methylphenidate compounds to enhance memory | SENTION INC. | 2002-09-19 | — | — | US | disclosed |
| US-20020103162-A1 | Use of threo-methylphenidate compounds to enhance memory | SENTION, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2002017920-A2 | USE OF METHYLPHENIDATE COMPOUNDS TO ENHANCE MEMORY | SENTION, INC (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2002017919-A2 | USE OF THREO-METHYLPHENIDATE COMPOUNDS TO ENHANCE MEMORY | SENTION, INC. (US) | 2002-03-07 | — | — | WO | disclosed |