Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182082 | 0.83 | TSHR (0.30) | TSHR | |
| SCHEMBL9185329 | 0.82 | AKR1B1 (0.41) | — | |
| SCHEMBL11202722 | 0.80 | IDO1 (0.38) | — | |
| SCHEMBL9181769 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL3825796 | 0.78 | MEN1 (0.31) | TSHR | |
| SCHEMBL7454500 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL7455345 | 0.75 | MEN1 (0.37) | — | |
| SCHEMBL9184390 | 0.75 | CYP1A2 (0.36) | — | |
| SCHEMBL15286577 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL9180692 | 0.74 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3694840-A1 | PIPERAZINE DERIVATIVES AS MAGL INHIBITORS | Hoffmann-La Roche AG (CH) | 2020-08-19 | — | — | EP | disclosed |
| WO-2019072785-A1 | PIPERAZINE DERIVATIVES AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-04-18 | — | — | WO | disclosed |
| EP-2099452-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | Mallinckrodt Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008061792-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| EP-0667868-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| EP-0091130-A2 | Cephalosporin derivatives, process for preparing and pharmaceutical compositions containing said compounds | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-10-12 | — | — | EP | disclosed |