Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 18/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.53 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460324 | 0.90 | ITGAV (0.53) | ITGAVITGB3ITGA2BITGA2 | |
| SCHEMBL382483 | 0.89 | ITGB3 (0.66) | ITGAVITGB3ITGA2B | |
| SCHEMBL382113 | 0.87 | ITGAV (0.53) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL383121 | 0.86 | ITGB3 (0.61) | ITGAVITGB3ITGA2B | |
| SCHEMBL382426 | 0.86 | ITGB3 (0.60) | ITGAVITGB3ITGA2B | |
| SCHEMBL383160 | 0.85 | ITGAV (0.58) | ITGAVITGB3ITGA2BITGA2 | |
| SCHEMBL382318 | 0.84 | ITGB3 (0.59) | ITGAVITGB3ITGA2B | |
| SCHEMBL382075 | 0.84 | ITGB3 (0.50) | ITGAVITGB3ITGA2BITGA2 | |
| SCHEMBL383206 | 0.84 | ITGB3 (0.51) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL383584 | 0.81 | ITGB3 (0.77) | ITGAVITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |