Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415667 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BDRD4NPC1GAA | |
| SCHEMBL382572 | 0.84 | ITGAV (0.53) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL7651216 | 0.78 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL460324 | 0.77 | ITGAV (0.53) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL382076 | 0.76 | DRD4 (0.51) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL383160 | 0.75 | ITGAV (0.58) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL383468 | 0.74 | ITGB3 (0.51) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL383213 | 0.73 | DRD4 (0.77) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL415668 | 0.73 | DRD4 (0.54) | ITGB3ITGA2BDRD4NPC1GAA | |
| SCHEMBL6500394 | 0.73 | ITGAV (0.50) | ITGB3ITGA2BITGAVKDM4EITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |