Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGAV | P06756 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 3/20 | 0.31 |
| ▸ | CDK4 | P11802 | 3/20 | 0.31 |
| ▸ | CCND1 | P24385 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GPR6 | P46095 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383781 | 0.88 | ITGB3 (0.36) | ITGB3ITGAVITGA2BCDK1CDK4 | |
| SCHEMBL382581 | 0.85 | ITGB3 (0.37) | ITGB3ITGAVITGA2BAOC3SYK | |
| SCHEMBL382680 | 0.85 | ITGB3 (0.51) | ITGB3ITGAVITGA2BTP53TSHR | |
| SCHEMBL381824 | 0.84 | ITGB3 (0.38) | ITGB3ITGAVITGA2BEPHX2 | |
| SCHEMBL381745 | 0.83 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL381748 | 0.80 | ITGB3 (0.38) | ITGB3ITGAVITGA2BEPHX2 | |
| SCHEMBL381746 | 0.79 | ITGB3 (0.41) | ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL383595 | 0.79 | ITGB3 (0.49) | ITGB3ITGAVITGA2BTP53TSHR | |
| SCHEMBL383782 | 0.78 | ITGB3 (0.36) | ITGB3ITGAVITGA2BGPR6 | |
| SCHEMBL382342 | 0.78 | ITGB3 (0.45) | ITGB3ITGAVITGA2BTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |