Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGAV | P06756 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382680 | 0.94 | ITGB3 (0.51) | ITGB3ITGAVITGA2BLMNATP53 | |
| SCHEMBL383596 | 0.86 | ITGB3 (0.43) | ITGB3ITGAVITGA2BLMNATP53 | |
| SCHEMBL382099 | 0.85 | ITGB3 (0.54) | ITGB3ITGAVITGA2BLMNATP53 | |
| SCHEMBL383234 | 0.83 | ITGB3 (0.69) | ITGB3ITGAVITGA2B | |
| SCHEMBL383237 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2BLMNAMAPT | |
| SCHEMBL382681 | 0.80 | ITGB3 (0.44) | ITGB3ITGAVITGA2BLMNATP53 | |
| SCHEMBL383235 | 0.79 | ITGB3 (0.48) | ITGB3ITGAVITGA2BLMNATSHR | |
| SCHEMBL382580 | 0.79 | ITGB3 (0.41) | ITGB3ITGAVITGA2BLMNATP53 | |
| SCHEMBL382492 | 0.78 | ITGB3 (0.70) | ITGB3ITGAVITGA2B | |
| SCHEMBL382927 | 0.78 | ITGB3 (0.76) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |