Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.44 |
| ▸ | ITGAV | P06756 | 9/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381814 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL383160 | 0.88 | ITGAV (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL6499264 | 0.82 | ITGAV (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL6501630 | 0.82 | ITGAV (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL6500457 | 0.81 | ITGAV (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL382418 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6498446 | 0.80 | ITGAV (0.48) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6507464 | 0.78 | ITGAV (0.45) | ITGB3ITGA2BITGAV | |
| SCHEMBL383097 | 0.78 | ITGAV (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL382801 | 0.78 | ITGAV (0.46) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |