Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 15/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496638 | 0.89 | ITGB3 (0.57) | ITGAVITGB3ITGA2B | |
| SCHEMBL383160 | 0.88 | ITGAV (0.58) | ITGAVITGB3ITGA2B | |
| SCHEMBL6499264 | 0.88 | ITGAV (0.49) | ITGAVITGB3ITGA2B | |
| SCHEMBL6497858 | 0.87 | ITGAV (0.54) | ITGAVITGB3ITGA2B | |
| SCHEMBL6500457 | 0.87 | ITGAV (0.47) | ITGAVITGB3ITGA2B | |
| SCHEMBL6507464 | 0.86 | ITGAV (0.45) | ITGAVITGB3ITGA2B | |
| SCHEMBL382801 | 0.86 | ITGAV (0.46) | ITGAVITGB3ITGA2B | |
| SCHEMBL6498446 | 0.86 | ITGAV (0.48) | ITGAVITGB3ITGA2B | |
| SCHEMBL382825 | 0.86 | ITGAV (0.61) | ITGAVITGB3ITGA2B | |
| SCHEMBL382622 | 0.82 | ITGB3 (0.44) | ITGAVITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | AJITO KEIICHI (JP) | 2005-03-17 | — | — | US | claimed |
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | AJITO KEIICHI (JP) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | ITGAV, ITGB3, ITGA4 | ITGAV 1/4885ITGB3 2/4885ITGA2B 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.