SCHEMBL3826754

SCHEMBL3826754

O=C(Oc1cccc(OC(=O)c2ccccc2)c1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.66
MAPT P10636 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
HSD17B10 Q99714 2/20 0.61
ESR1 P03372 2/20 0.61
ESR2 Q92731 2/20 0.61
MEN1 O00255 1/20 0.61
JAK2 O60674 1/20 0.61
USP2 O75604 1/20 0.61
GAA P10253 1/20 0.61
ALOX15 P16050 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
SLC6A3 Q01959 1/20 0.58
LMNA P02545 2/20 0.56
METAP2 P50579 1/20 0.56
METAP1 P53582 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
TOP1 P11387 1/20 0.56
SLC2A1 P11166 1/20 0.54
SLC2A4 P14672 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15283463 0.87 KMT2A (0.56) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL6939316 0.87 KMT2A (0.56) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL2886267 0.87 SLC2A1 (0.72) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL725404 0.87 KMT2A (0.76) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL28218043 0.86 SLC6A3 (0.57) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL2484009 0.86 TOP1 (0.55) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL28412672 0.86 SLC6A3 (0.57) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
Hydrochloric Acid SCHEMBL16050041 0.85 KMT2A (0.73) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
Bromide SCHEMBL29588519 0.85 KMT2A (0.73) KMT2AMAPTSMN1; SMN2HSD17B10ESR1
SCHEMBL9789626 0.84 KMT2A (0.54) KMT2AMAPTSMN1; SMN2HSD17B10ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957571-B1 STABILIZED THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM GEN ELECTRIC (US) 2009-09-16 EP disclosed
US-7511092-B2 bisphenol a type polycarbonates (e.g. polyesterpolycarbonate copolymer), pyrogallol tri-benzoate (PTB), and pyrogallol tri-phenyl carbonate (PTPC), and an ionization inhibitor ( 2-Methyl-2,4-pentanediol ); improved resistance to gamma-rays SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-03-31 US disclosed
EP-1957571-A2 STABILIZED THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM General Electric Company (US) 2008-08-20 EP disclosed
WO-2007044303-A2 STABILIZED THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-04-19 WO disclosed
US-20070082989-A1 Stabilized thermoplastic composition, method of making, and articles formed therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-04-12 US disclosed
EP-0699543-B1 Printing paper SONY CORP (JP) 1999-12-01 EP disclosed
US-5635441-A SHEET SUBSTRATE HAVING DYE RECEIVING LAYER OF CROSSLINKED COATING OBTAINED BY CURING MIXTURE OF BUTYRAL RESIN, VINYLPHENOLIC RESIN, POLYISOCYANATE; STORAGE STABLE IMAGES SONY CORPORATION (JP) 1997-06-03 US disclosed
EP-0699543-A1 Printing paper SONY CORPORATION (JP) 1996-03-06 EP disclosed
US-5294484-A Multilayer element SONY CORPORATION (JP) 1994-03-15 US disclosed