Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 13/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 13/20 | 0.55 |
| ▸ | RELA | Q04206 | 13/20 | 0.55 |
| ▸ | IKBKB | O14920 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381990 | 0.81 | RELA (0.61) | NFKB1NFKB2RELAIKBKBPOLB | |
| SCHEMBL6383039 | 0.70 | PTPN1 (0.54) | RELAPOLBPTPN1USP2 | |
| Lantanilic Acid SCHEMBL30014810 | 0.68 | NFKB1 (0.69) | NFKB1NFKB2RELAIKBKBBCL2L1 | |
| Camaric Acid SCHEMBL30014910 | 0.67 | NFKB1 (0.68) | NFKB1NFKB2RELAIKBKBBCL2L1 | |
| SCHEMBL30308940 | 0.66 | NFKB1 (0.66) | NFKB1NFKB2RELAIKBKBPOLB | |
| Acetyl Oleanolic Acid SCHEMBL23284080 | 0.66 | PTPN1 (1.00) | RELAPOLBPTPN1USP2 | |
| SCHEMBL25132324 | 0.66 | MEN1 (0.81) | POLBPTPN1USP2 | |
| SCHEMBL20640288 | 0.66 | MEN1 (0.81) | POLBPTPN1USP2 | |
| SCHEMBL23610479 | 0.66 | MEN1 (0.81) | POLBPTPN1USP2 | |
| Acetyl Oleanolic Acid SCHEMBL22151955 | 0.66 | PTPN1 (1.00) | RELAPOLBPTPN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503773-B9 | HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID | COUNCIL SCIENT IND RES (IN) | 2012-01-25 | — | — | EP | disclosed |
| EP-1503773-B1 | HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID | COUNCIL SCIENT IND RES (IN) | 2011-03-30 | — | — | EP | disclosed |
| EP-1509223-B1 | HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN | COUNCIL SCIENT IND RES (IN) | 2008-08-20 | — | — | EP | disclosed |
| US-7259148-B2 | Hepatoprotective activity of 2′-p-hydroxybenzoylmussaenosidic acid | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-08-21 | — | — | US | disclosed |
| US-20040029816-A1 | Hepatoprotective activity of 10-O-P-hydroxybenzoyiaucubin | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-02-12 | — | — | US | disclosed |
| US-20040014684-A1 | Hepatoprotective activity of 2'-p-hydroxybenzoylmussaenosidic | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-01-22 | — | — | US | disclosed |