Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8698940 | 0.60 | — | — | |
| Water SCHEMBL14720941 | 0.60 | — | — | |
| Bromide SCHEMBL6247121 | 0.58 | CA1 (0.41) | — | |
| SCHEMBL12997531 | 0.58 | CES2 (0.35) | — | |
| SCHEMBL14175184 | 0.57 | CES2 (0.30) | — | |
| Bromide SCHEMBL29142804 | 0.56 | CA1 (0.39) | — | |
| Bromide SCHEMBL8559956 | 0.56 | CA1 (0.39) | — | |
| SCHEMBL12917833 | 0.55 | ESR2 (0.32) | — | |
| SCHEMBL6302303 | 0.55 | TSHR (0.42) | — | |
| Potassium Ion SCHEMBL31034634 | 0.54 | CA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102155-A1 | ARYL COMPOUNDS AS PPAR LIGANDS AND THEIR USE | Seoul National University Industry Foundation (KR) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008066356-A1 | ARYL COMPOUNDS AS PPAR LIGANDS AND THEIR USE | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-06-05 | — | — | WO | disclosed |