Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575172 | 0.94 | RAB9A (0.64) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL11215847 | 0.85 | RAB9A (0.53) | RAB9AKDM4ENPC1SMN1; SMN2CHRNA7 | |
| SCHEMBL11215851 | 0.85 | RAB9A (0.53) | RAB9AKDM4ENPC1SMN1; SMN2CHRNA7 | |
| SCHEMBL1364377 | 0.81 | RAB9A (0.38) | RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1685304 | 0.80 | RAB9A (0.52) | RAB9AKDM4ENPC1SMN1; SMN2CHRNA7 | |
| SCHEMBL4533210 | 0.80 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL1366222 | 0.80 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL18532429 | 0.77 | RAB9A (0.64) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL2973096 | 0.77 | RAB9A (0.87) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL7160184 | 0.77 | RAB9A (0.87) | RAB9AKDM4ENPC1SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853719-B1 | ENZYMATIC TRANSFORMATION OF A PROSTAGLANDIN (BIMATOPROST) INTERMEDIATE | TEVA PHARMA (IL) | 2009-09-02 | — | — | EP | disclosed |