SCHEMBL382803

SCHEMBL382803

O=C(O)c1cc(Br)c(O)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.49
AKR1C4 P17516 1/20 0.48
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48
AKR1C1 Q04828 1/20 0.48
HSP90AA1 P07900 1/20 0.47
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA12 O43570 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
ALDH1A1 P00352 3/20 0.46
PTGS2 P35354 2/20 0.46
ALOX5 P09917 1/20 0.46
TSHR P16473 1/20 0.46
PTPN1 P18031 2/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29592373 1.00 GPR35 (0.49) GPR35AKR1C4AKR1C3AKR1C2AKR1C1
Water SCHEMBL3706268 0.98 GPR35 (0.47) GPR35AKR1C4AKR1C3AKR1C2AKR1C1
Water SCHEMBL31258845 0.98 GPR35 (0.47) GPR35AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL9478732 0.88 AKR1C4 (0.50) AKR1C4AKR1C3AKR1C2AKR1C1CA1
SCHEMBL31169213 0.88 AKR1C4 (0.50) GPR35AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL2985505 0.86 CA1 (0.53) AKR1C4AKR1C3AKR1C2AKR1C1CA1
SCHEMBL460201 0.82 CA1 (0.56) CA1CA2CA12CA7CA9
SCHEMBL1669745 0.81 ALDH1A1 (0.63) AKR1C4AKR1C3AKR1C2AKR1C1HSP90AA1
SCHEMBL24760837 0.80 AKR1C2 (0.48) GPR35AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL1976832 0.80 CA1 (0.45) AKR1C4AKR1C3AKR1C2AKR1C1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-117310031-B Method for detecting halogenated organic pollutants in animal food 东莞理工学院 2024-07-12 CN claimed
CN-117310031-A Method for detecting halogenated organic pollutants in animal food 东莞理工学院 2023-12-29 CN claimed
CN-117310039-A Method for detecting halogenated organic pollutants in plastic of electronic and electrical product 东莞理工学院 2023-12-29 CN claimed
CN-117233299-A Method for detecting halogenated polyphenol in drinking water by solid phase extraction-vacuum centrifugal concentration-liquid chromatography tandem mass spectrometry 浙江大学 2023-12-15 CN claimed
CN-113816940-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-21 CN claimed
CN-113754634-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-07 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
CN-103838086-B The composition of the formation antireflection film of reaction product containing isocyanuric acid compound and benzoic acid compounds 日产化学工业株式会社 2017-10-20 CN claimed
CN-103838086-A Composition containing reaction product of isocyanuric acid compound and benzoic acid compound for forming anti-reflection film NISSAN CHEMICAL IND LTD 2014-06-04 CN claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-20090117493-A1 Anti-Reflective Coating Forming Composition Containing Reaction Product of Isocyanuric Acid Compound with Benzoic Acid Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-05-07 US claimed
CN-101268419-A Composition for forming antireflection film containing reaction product of isocyanuric acid compound and benzoic acid compound NISSAN CHEMICAL INDUSTRY LTD (JP) 2008-09-17 CN claimed
EP-1939688-A1 COMPOSITION FOR ANTIREFLECTION FILM FORMATION, COMPRISING PRODUCT OF REACTION BETWEEN ISOCYANURIC ACID COMPOUND AND BENZOIC ACID COMPOUND Nissan Chemical Industries, Ltd. (JP) 2008-07-02 EP claimed
EP-1697732-A1 ANALYTE INJECTION SYSTEM Caliper Life Sciences, Inc. (US) 2006-09-06 EP claimed
WO-2005068993-A1 ANALYTE INJECTION SYSTEM CALIPER LIFE SCIENCES, INC. (US) 2005-07-28 WO claimed
US-20050133370-A1 Analyte injection system CALIPER LIFE SCIENCES, INC. (US) 2005-06-23 US claimed
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS GPR35 4703/4885AKR1C4 3835/4885AKR1C3 4367/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS GPR35 4703/4885AKR1C4 3835/4885AKR1C3 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.