Styrene

Styrene

SCHEMBL3828345

C=C(C#N)CC.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TSHR P16473 1/20 0.47
POLB P06746 2/20 0.34
MAPT P10636 4/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
MCL1 Q07820 2/20 0.33
MAPK1 P28482 1/20 0.33
CYP3A4 P08684 1/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
PLIN1 O60240 1/20 0.31
LMNA P02545 1/20 0.31
PLIN5 Q00G26 1/20 0.31
ABHD5 Q8WTS1 1/20 0.31
KDM1A O60341 1/20 0.31
PKM P14618 1/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7644648 0.83 ALDH1A1 (0.47) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL353087 0.82 ALDH1A1 (0.54) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL16194120 0.82 ALDH1A1 (0.58) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL1003442 0.81 ALDH1A1 (0.44) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL27694327 0.80 ALDH1A1 (0.56) ALDH1A1TSHRPOLBTP53TDP1
Styrene SCHEMBL27752708 0.80 ALDH1A1 (0.67) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL28774655 0.79 ALDH1A1 (0.54) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL353852 0.78 ALDH1A1 (0.58) ALDH1A1TSHRPOLBMAPTNPC1
Styrene SCHEMBL15104462 0.78 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4TP53TDP1
Styrene SCHEMBL27445653 0.78 ALDH1A1 (0.58) ALDH1A1TSHRPOLBMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060178466-A1 Nanocomposite composition having barrier property KIM MYUNG H 2006-08-10 US claimed
EP-1797137-A4 NANOCOMPOSITE COMPOSITION HAVING BARRIER PROPERTY LG CHEMICAL LTD (KR) 2009-07-29 EP disclosed
CN-101035849-A Nanocomposite composition with barrier properties LG CHEMICAL LTD (KR) 2007-09-12 CN disclosed
EP-1797137-A1 NANOCOMPOSITE COMPOSITION HAVING BARRIER PROPERTY LG Chem, Ltd. (KR) 2007-06-20 EP disclosed
US-20060178466-A1 Nanocomposite composition having barrier property KIM MYUNG H 2006-08-10 US disclosed
WO-2006080683-A1 NANOCOMPOSITE COMPOSITION HAVING BARRIER PROPERTY LG CHEM, LTD. (KR) 2006-08-03 WO disclosed