Styrene

Styrene

SCHEMBL1003442

C=C(C#N)CCCC.C=Cc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
PTGS2 P35354 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
POLB P06746 1/20 0.33
EGFR P00533 1/20 0.33
HDAC3 O15379 1/20 0.33
ESR1 P03372 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3828345 0.81 ALDH1A1 (0.47) ALDH1A1TSHRLMNATDP1POLB
Styrene SCHEMBL14058497 0.80 PTGS2 (0.40) ALDH1A1TSHRLMNATDP1PTGS2
Styrene SCHEMBL183141 0.80 LMNA (0.41) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL6910024 0.79 ALDH1A1 (0.48) ALDH1A1TSHRLMNATDP1PTGS2
Styrene SCHEMBL5270544 0.78 LMNA (0.47) ALDH1A1TSHRLMNATDP1PTGS2
Styrene SCHEMBL258132 0.78 LMNA (0.47) ALDH1A1TSHRLMNATDP1PTGS2
Styrene SCHEMBL5287077 0.78 ALDH1A1 (0.47) ALDH1A1TSHRLMNATDP1PTGS2
Styrene SCHEMBL17065130 0.78 LMNA (0.47) ALDH1A1TSHRLMNATDP1PTGS2
Styrene SCHEMBL11801013 0.77 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL10715462 0.77 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110008637-A1 METHOD FOR IMPROVING THE PERFORMANCE OF OPTICAL BRIGHTENING AGENTS NALCO COMPANY 2011-01-13 US disclosed
WO-2011005805-A2 METHOD FOR IMPROVING THE PERFORMANCE OF OPTICAL BRIGHTENING AGENTS NALCO COMPANY (US) 2011-01-13 WO disclosed
US-6617386-B2 For the exterior of a building or structure; textured finish DRYVIT SYSTEMS, INC. 2003-09-09 US disclosed
US-20030055147-A1 For the exterior of a building or structure; textured finish DRYVIT SYSTEMS, INC. 2003-03-20 US disclosed