SCHEMBL3828370

SCHEMBL3828370

CC(C)(C)OO[Si](OOC(C)(C)C)(OOC(C)(C)C)OOC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28441174 0.87 TSHR (0.39) TSHRTDP1ALDH1A1
SCHEMBL28096516 0.81 TSHR (0.33) TSHRTDP1
SCHEMBL6693652 0.79 TSHR (0.44) TSHRTDP1
SCHEMBL28529208 0.79 TSHR (0.32) TSHRTDP1
SCHEMBL7076677 0.79 TSHR (0.32) TSHRTDP1
SCHEMBL28148421 0.76 TSHR (0.35) TSHRTDP1
SCHEMBL388352 0.74 TSHR (0.47) TSHRTDP1
SCHEMBL774989 0.74 TSHR (0.47) TSHRTDP1
SCHEMBL388565 0.74 TSHR (0.47) TSHRTDP1
SCHEMBL1345915 0.72 TSHR (0.44) TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10232344-B2 Solid sorbent materials for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2019-03-19 US claimed
US-20170197198-A1 SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2017-07-13 US claimed
US-9402933-B2 Structured coatings for implants and process for the preparation thereof BIOCER ENTWICKLUNGS GMBH (DE) 2016-08-02 US claimed
EP-2063922-B1 STRUCTURED COATINGS FOR IMPLANTS AND METHOD FOR PRODUCTION THEREOF BIOCER ENTWICKLUNGS GMBH (DE) 2012-07-11 EP claimed
US-20090317766-A1 Structured coatings for implants and process for the preparation thereof BIOCER ENTWICKLUNGS GMBH (DE) 2009-12-24 US claimed
US-20200368389-A1 THREE-DIMENSIONAL STRUCTURE, METHOD FOR PRODUCING SAME, AND COATING DEVICE ISHIHARA SANGYO KAISHA, LTD. (JP) 2020-11-26 US disclosed
EP-3663082-A1 THREE-DIMENSIONAL STRUCTURE, METHOD FOR MANUFACTURING SAME, AND COATING DEVICE Ishihara Sangyo Kaisha, Ltd. (JP) 2020-06-10 EP disclosed
US-10232344-B2 Solid sorbent materials for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2019-03-19 US disclosed
US-20170197198-A1 SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2017-07-13 US disclosed
WO-2016011032-A1 SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2016-01-21 WO disclosed
US-4357266-A Flexible resistor compositions SHIN-ETSU POLYMER CO., LTD. (JP) 1982-11-02 US disclosed