SCHEMBL388565

SCHEMBL388565

CC(C)(C)OO[Si](C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL774989 0.79 TSHR (0.47) TSHRTDP1
SCHEMBL388352 0.79 TSHR (0.47) TSHRTDP1
SCHEMBL3828370 0.74 TSHR (0.50) TSHRTDP1
SCHEMBL31432779 0.73 TSHR (0.41) TSHRTDP1
SCHEMBL6228909 0.71
SCHEMBL9812976 0.69 TSHR (0.37) TSHRTDP1
SCHEMBL9813037 0.69 TSHR (0.37) TSHRTDP1
SCHEMBL9813035 0.69 TSHR (0.37) TSHRTDP1
SCHEMBL11251310 0.69 TSHR (0.41) TSHRTDP1
SCHEMBL1345915 0.69 TSHR (0.44) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117844311-A EAA emulsion special for stone paper and preparation method thereof 海南必凯水性新材料有限公司 2024-04-09 CN claimed
CN-117352955-A High-porosity wet-process diaphragm and preparation method and application thereof 河北金力新能源科技股份有限公司 2024-01-05 CN claimed
US-20170102347-A1 BIOCHEMICAL TEST CHIP APEX BIOTECHNOLOGY CORP. (TW) 2017-04-13 US claimed
EP-3153857-A1 BIOCHEMICAL TEST CHIP Apex Biotechnology Corporation (TW) 2017-04-12 EP claimed
US-20160178813-A1 PHOTOSENSITIVE RESIN COMPOSITION AND USES THEREOF CHI MEI CORPORATION (TW) 2016-06-23 US claimed
US-8173048-B2 Composition for circuit connection film and circuit connection film using the same CHEIL INDUSTRIES, INC. (KR) 2012-05-08 US claimed
US-20100148130-A1 Composition for circuit connection film and circuit connection film using the same KUKDO ADVANCED MATERIALS CO., LTD. (KR) 2010-06-17 US claimed
US-20090298667-A1 Controlled Gas Pore Formers in Extruded Ware CORNING INCORPORATED 2009-12-03 US claimed
US-12617940-B2 Curable composition and cured material COSMO OIL LUBRICANTS CO., LTD. (JP) 2026-05-05 US disclosed
US-12606655-B2 Curable resin, curable resin composition, and cured product DIC CORPORATION (JP) 2026-04-21 US disclosed
US-12577432-B2 Organosilicon compound, production method therefor, and curable composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-17 US disclosed
EP-4282653-B1 ORGANOSILICON COMPOUND, PRODUCTION METHOD THEREFOR, AND CURABLE COMPOSITION SHINETSU CHEMICAL CO (JP) 2026-02-25 EP disclosed
US-20250326950-A1 SILSESQUIOXANE DERIVATIVE AND METHOD FOR PRODUCING SAME, CURABLE COMPOSITION, HARD COAT AGENT, CURED PRODUCT, HARD COAT, AND BASE MATERIAL TOAGOSEI CO LTD (JP) 2025-10-23 US disclosed
CN-119798756-B Preparation method of polypropylene film for labels 浙江南洋华诚科技股份有限公司 2025-06-13 CN disclosed
EP-0431881-A2 Fabric material coated with a self-adhesive silicone rubber SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-12 EP disclosed
US-5021533-A Intermediate for silicon nitride ceramics HERCULES INCORPORATED (US) 1991-06-04 US disclosed
US-4814408-A SILYLBENZOYL PEROXIDE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1989-03-21 US disclosed
US-4681636-A T-BUTYLPEROXYSILANE, DI- OR POLYALKOXY SILICON COMPOUND, ORGANOTITANATE ESTER, SOLVENT TORAY SILICONE CO., LTD. (JP) 1987-07-21 US disclosed
EP-0207634-A2 Bonding primer composition Toray Silicone Company, Ltd. (JP) 1987-01-07 EP disclosed
US-4357266-A Flexible resistor compositions SHIN-ETSU POLYMER CO., LTD. (JP) 1982-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577432-B2 Organosilicon compound, production method therefor, and curable composition ASH2L, DOT1L, DNMT3L TSHR 4783/4885TDP1 3128/4885
US-12606655-B2 Curable resin, curable resin composition, and cured product ARCN1, CAPZA1, CAPZB TSHR 1968/4885TDP1 2616/4885
US-12617940-B2 Curable composition and cured material MAT2B, MMAB, RAD51 TSHR 3577/4885TDP1 1524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.