SCHEMBL388352

SCHEMBL388352

CC(C)(C)OO[Si](C)(C)OOC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388565 0.79 TSHR (0.47) TSHRTDP1
SCHEMBL774989 0.79 TSHR (0.47) TSHRTDP1
SCHEMBL3828370 0.74 TSHR (0.50) TSHRTDP1
SCHEMBL31432779 0.73 TSHR (0.41) TSHRTDP1
SCHEMBL9813035 0.69 TSHR (0.37) TSHRTDP1
SCHEMBL9813037 0.69 TSHR (0.37) TSHRTDP1
SCHEMBL9812976 0.69 TSHR (0.37) TSHRTDP1
SCHEMBL1345915 0.69 TSHR (0.44) TSHRTDP1
SCHEMBL23630874 0.67 TSHR (0.35) TSHRTDP1
SCHEMBL1404386 0.67 TSHR (0.35) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101117-B2 Controlled gas pore formers in extruded ware CORNING, INCORPORATED (US) 2012-01-24 US claimed
US-20090298667-A1 Controlled Gas Pore Formers in Extruded Ware CORNING INCORPORATED 2009-12-03 US claimed
US-8101117-B2 Controlled gas pore formers in extruded ware CORNING, INCORPORATED (US) 2012-01-24 US disclosed
US-20090298667-A1 Controlled Gas Pore Formers in Extruded Ware CORNING INCORPORATED 2009-12-03 US disclosed
EP-0207634-B1 BONDING PRIMER COMPOSITION Toray Silicone Company, Ltd. (JP) 1991-08-07 EP disclosed
US-4681636-A T-BUTYLPEROXYSILANE, DI- OR POLYALKOXY SILICON COMPOUND, ORGANOTITANATE ESTER, SOLVENT TORAY SILICONE CO., LTD. (JP) 1987-07-21 US disclosed
EP-0207634-A2 Bonding primer composition Toray Silicone Company, Ltd. (JP) 1987-01-07 EP disclosed
EP-0009070-B1 T-OCTYL SILICON PEROXIDES AND THEIR USE FOR CROSSLINKING POLYETHYLENES Argus Chemical Corporation (US) 1981-09-23 EP disclosed
US-4245056-A Crosslinking high density polyethylene with t-octyl silicon peroxides ARGUS CHEMICAL CORPORATION (US) 1981-01-13 US disclosed
US-4198337-A CURING CATALYSTS ARGUS CHEMICAL CORPORATION (US) 1980-04-15 US disclosed
EP-0009070-A1 t-Octyl silicon peroxides and their use for crosslinking polyethylenes Argus Chemical Corporation (US) 1980-04-02 EP disclosed
US-4148954-A THERMOPLASTICS AT LOW PRESSURE UNION CARBIDE CORPORATION (US) 1979-04-10 US disclosed