Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828368 | 1.00 | ALOX15 (0.39) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL22980099 | 0.79 | LMNA (0.44) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL16244419 | 0.79 | ALOX15 (0.39) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL1487052 | 0.79 | LMNA (0.44) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL1487054 | 0.79 | LMNA (0.44) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL28085798 | 0.79 | ALOX15 (0.35) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL29102680 | 0.78 | — | — | |
| SCHEMBL29102681 | 0.78 | — | — | |
| SCHEMBL3157434 | 0.76 | ALOX15 (0.37) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL3161147 | 0.76 | ALOX15 (0.37) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099756-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |