⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18013198 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL10039507 | 0.74 | — | — | |
| SCHEMBL1925147 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL30581182 | 0.73 | — | — | |
| SCHEMBL2415 | 0.73 | — | — | |
| SCHEMBL1332099 | 0.73 | — | — | |
| SCHEMBL1190178 | 0.73 | — | — | |
| SCHEMBL4820393 | 0.73 | — | — | |
| SCHEMBL30581185 | 0.73 | — | — | |
| SCHEMBL22062701 | 0.72 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3895707-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2023-10-04 | — | — | EP | disclosed |
| EP-3895707-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-10-20 | — | — | EP | disclosed |
| CN-113164771-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-2240276-B1 | IRON AND COPPER CATALYTIC SYSTEMS FOR CROSS-COUPLING REACTIONS | CENTRE NAT RECH SCIENT (FR) | 2020-12-02 | — | — | EP | disclosed |
| US-9861971-B2 | Catalytic system for cross-coupling reactions | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-01-09 | — | — | US | disclosed |
| US-20160130205-A1 | CATALYTIC SYSTEM FOR CROSS-COUPLING REACTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2016-05-12 | — | — | US | disclosed |
| US-9272274-B2 | Catalytic system for cross-coupling reactions | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2016-03-01 | — | — | US | disclosed |
| US-9162953-B2 | Iron-copper co-catalyzed process for carbon-carbon or carbon-heteroatom bonding | CENTRE NATIONALE DE RECHERCHE SCIENTIFIQUE (FR) | 2015-10-20 | — | — | US | disclosed |
| US-20140329946-A1 | RUBBER COMPOSITION AND MANUFACTURING METHOD FOR SAME | BRIDGESTONE CORPORATION (JP) | 2014-11-06 | — | — | US | disclosed |
| US-8674125-B2 | Method for the preparation of phosphine butadiene ligands, complexes thereof with copper and use thereof in catalysis | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2014-03-18 | — | — | US | disclosed |
| US-5942504-A | INHIBITORS OF RETROVIRAL PROTEASES; TREATMENT OF AIDS AND HIV | NARHEX LIMITED (HK) | 1999-08-24 | — | — | US | disclosed |
| US-5679688-A | RETROVIRAL PROTEASE INHIBITORS; AIDS THERAPY | NARHEX LIMITED (HK) | 1997-10-21 | — | — | US | disclosed |
| US-5433896-A | FLUORESCENT | MOLECULAR PROBES, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| EP-0633881-A4 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0633881-A1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | Narhex Limited (HK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993018006-A1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | NARHEX LIMITED (HK) | 1993-09-16 | — | — | WO | disclosed |
| EP-0294258-A1 | Hydrazine derivatives, process for obtaining them and pharmaceutical composition containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-12-07 | — | — | EP | disclosed |
| US-4500539-A | APHIDS, COCKROACHES | CHEVRON RESEARCH COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4499098-A | Insecticidal N-carbamoyl-oxadiazolidin-5-ones and thiones | CHEVRON RESEARCH COMPANY (US) | 1985-02-12 | — | — | US | disclosed |
| US-4045484-A | FROM ACETHYDRAZIDE, FORMALDEHYDE AND HYDROGEN IN A PALLADIUM CATALYST | UNIROYAL, INC. (US) | 1977-08-30 | — | — | US | disclosed |