Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173378 | 0.83 | MTNR1A (0.50) | LOXL2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL15109307 | 0.83 | MTNR1A (0.50) | LOXL2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL16756017 | 0.78 | LOXL2 (0.63) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL15902409 | 0.78 | LOXL2 (0.67) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL9679411 | 0.77 | MTNR1A (0.64) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL11623541 | 0.76 | MTNR1A (0.62) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL15224006 | 0.75 | MTNR1A (0.65) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL29390774 | 0.75 | LOXL2 (0.63) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL1331625 | 0.75 | LOXL2 (0.63) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL13091580 | 0.75 | MTNR1A (0.61) | LOXL2MTNR1AMTNR1BPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268640-B1 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE INDOLOPYRIDINES | 4SC AG (DE) | 2016-10-12 | — | — | EP | disclosed |
| EP-2098524-A1 | Process for preparing enantiomerically pure indolopyrinidines | 4SC AG (DE) | 2009-09-09 | — | — | EP | disclosed |