Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567642 | 1.00 | PIK3CD (0.43) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL9046864 | 0.87 | SMN1; SMN2 (0.40) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL4165718 | 0.86 | PIK3CD (0.43) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL31086606 | 0.82 | ADRB2 (0.52) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL19943572 | 0.82 | CYP3A4 (0.45) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL31247543 | 0.82 | ADRB2 (0.52) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL14211414 | 0.82 | ADRB2 (0.52) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL594241 | 0.82 | ADRB2 (0.52) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL4092765 | 0.82 | ADRB2 (0.52) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 | |
| Hydrochloric Acid SCHEMBL14121259 | 0.80 | ADRB2 (0.50) | PIK3CDADRA2AADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | TP53, MDM2, TP53BP1 | PIK3CD 3385/4885ADRA2A 3954/4885ADRA2B 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.