Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086606 | 1.00 | ADRB2 (0.52) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| SCHEMBL4092765 | 1.00 | ADRB2 (0.52) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| SCHEMBL31247543 | 1.00 | ADRB2 (0.52) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| SCHEMBL14211414 | 1.00 | ADRB2 (0.52) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL14121259 | 0.98 | ADRB2 (0.50) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL14121000 | 0.98 | ADRB2 (0.50) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL14157129 | 0.98 | ADRB2 (0.50) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| SCHEMBL9046864 | 0.83 | SMN1; SMN2 (0.40) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 | |
| SCHEMBL1090665 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2PIK3CDCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL3828644 | 0.82 | PIK3CD (0.43) | ADRB2SMN1; SMN2PIK3CDCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737875-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-08-22 | — | — | US | claimed |
| WO-2021255093-A1 | ACTIVE COMPOUND COMBINATION | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-23 | — | — | WO | disclosed |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-20170360041-A1 | N-[1-((6-CHLOROPYRIDIN-3-YL)METHYL)PYRIDIN-2(1H)-YLIDENE]-2,2,2- TRIFLUOROACETAMIDE FOR CONTROL OF AGRICULTURAL/HORTICULTURAL PESTS | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-9717242-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2-trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20160205933-A1 | PEST CONTROL AGENT | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-07-21 | — | — | US | disclosed |
| US-9328068-B2 | N-[1-((6-chloropyridin-3-yl) methyl)pyridin-2(1H)-ylidene]-2,2,2-trifluoroacetamide for control of animal parasitic pests and agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| EP-2984930-A1 | PEST CONTROL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| EP-2631235-B1 | Pest control agent | MEIJI SEIKA PHARMA CO LTD (JP) | 2016-02-10 | — | — | EP | disclosed |
| EP-2959775-A1 | PEST CONTROL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-20070117798-A1 | Morpholine type cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-RE35811-E | PESTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-26 | — | — | US | disclosed |
| CN-1031265-C | Tetrahydropyrimidine-containing pest control compositions | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0375907-B1 | Insecticidally active nitro compounds | BAYER AGROCHEM KK (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5238949-A | Insecticidally active nitro pyridyl compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1993-08-24 | — | — | US | disclosed |
| US-5204359-A | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5084467-A | INSECTICIDALLY ACTIVE NITRO GUANIDINE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5051434-A | Pyridyl, thiazolyl, thiadiazolyl, pyrimidinyl or isooxazolyl groups | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-09-24 | — | — | US | disclosed |
| EP-0383091-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-08-22 | — | — | EP | disclosed |
| EP-0375907-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117798-A1 | Morpholine type cinnamide compound | MLX, XDH, NOX4 | ADRB2 95/4885SMN1; SMN2 642/4885PIK3CD 4406/4885 |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | NR2E1, CROCC, PRMT1 | ADRB2 427/4885SMN1; SMN2 1892/4885PIK3CD 3278/4885 |
| US-20170360041-A1 | N-[1-((6-CHLOROPYRIDIN-3-YL)METHYL)PYRIDIN-2(1H)-YLIDENE]-2,2,2- TRIFLUOROACETAMIDE FOR CONTROL OF AGRICULTURAL/HORTICULTURAL PESTS | NR2E1, CROCC, PRMT1 | ADRB2 427/4885SMN1; SMN2 1892/4885PIK3CD 3278/4885 |
| US-20160205933-A1 | PEST CONTROL AGENT | RPS4Y1, RPS4X, RDX | ADRB2 999/4885SMN1; SMN2 2292/4885PIK3CD 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.