Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 8/20 | 0.35 |
| ▸ | PLAU | P00749 | 8/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828854 | 0.88 | FABP4 (0.40) | EPHX2FABP4DPP8FABP3FABP5 | |
| SCHEMBL3826729 | 0.86 | DPP8 (0.35) | EPHX2FABP4DPP8FABP3FABP5 | |
| SCHEMBL3829057 | 0.80 | SMN1; SMN2 (0.46) | DPP8ALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL13964831 | 0.74 | PLAU (0.43) | PLGPLAUF10ST14F2 | |
| SCHEMBL4526832 | 0.72 | EPHX2 (0.43) | EPHX2FABP4DPP8FABP3FABP5 | |
| SCHEMBL3825976 | 0.67 | FABP4 (0.49) | EPHX2FABP4DPP8FABP3FABP5 | |
| SCHEMBL3831668 | 0.66 | FABP4 (0.47) | EPHX2FABP4DPP8FABP3FABP5 | |
| SCHEMBL3831673 | 0.66 | FABP4 (0.47) | EPHX2FABP4DPP8FABP3FABP5 | |
| SCHEMBL17611077 | 0.66 | FABP3 (0.50) | FABP4FABP3FABP5ALDH1A1PSEN1 | |
| SCHEMBL4530837 | 0.65 | EPHX2 (0.44) | EPHX2FABP4DPP8FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099747-A1 | RADIOLABELLING VIA FLUORINATION OF AZIRIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-09-16 | — | — | EP | disclosed |
| US-20090022664-A1 | Radiolabelling via fluorination of aziridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090022664-A1 | Radiolabelling via fluorination of aziridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090022664-A1 | Radiolabelling via fluorination of aziridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-22 | — | — | US | disclosed |
| WO-2008083729-A1 | RADIOLABELLING VIA FLUORINATION OF AZIRIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008083729-A1 | RADIOLABELLING VIA FLUORINATION OF AZIRIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | WO | disclosed |
| EP-1944288-A1 | Radiolabelling via fluorination of aziridines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-07-16 | — | — | EP | disclosed |
| EP-1944288-A1 | Radiolabelling via fluorination of aziridines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022664-A1 | Radiolabelling via fluorination of aziridines | TMEM14C, ARFGEF1, NPFFR1 | EPHX2 1030/4885FABP4 2380/4885DPP8 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.