Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470456 | 0.92 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL10943449 | 0.92 | TSHR (0.56) | TSHRMAPK1MEN1KMT2ACA2 | |
| SCHEMBL2471478 | 0.89 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ACA2 | |
| SCHEMBL11754046 | 0.89 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ACA2 | |
| SCHEMBL10943454 | 0.89 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ACA2 | |
| SCHEMBL6150504 | 0.89 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ACA2 | |
| SCHEMBL76625 | 0.87 | — | — | |
| SCHEMBL29768835 | 0.87 | — | — | |
| SCHEMBL7358305 | 0.85 | GAA (0.38) | TSHRMAPK1MEN1KMT2ACA2 | |
| Phosphine SCHEMBL21227051 | 0.84 | CA2 (0.42) | TSHRCA2CA9ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517868-A1 | CEMENT ADMIXTURE HAVING SUPERIOR WATER-REDUCING PROPERTIES AND METHOD FOR PREPARING THE SAME | LG Chem, Ltd. (KR) | 2005-03-30 | — | — | EP | claimed |
| WO-2004002917-A1 | CEMENT ADMIXTURE HAVING SUPERIOR WATER-REDUCING PROPERTIES AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2004-01-08 | — | — | WO | claimed |
| US-20090105320-A1 | Biodal Compositions Containing 1,2-Benzisothiazolin-3-One And 1,2-Dibromo-2,4-Dicyanobutane | CLARIANT FINANCE (BVI) LTD. (VG) | 2009-04-23 | — | — | US | disclosed |
| US-20080045824-A1 | SILICONE COMPOSITION FOR BIOCOMPATIBLE MEMBRANE | DEXCOM, INC. (US) | 2008-02-21 | — | — | US | disclosed |
| US-7166341-B2 | of olefinically unsaturated monomers, including esters of dicarboxy acids, onto polyalkylene oxides containing a resin which improves tackiness and compatibility of the adhesive; use in the labelling of recyclable or reuseable hollow containers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-23 | — | — | US | disclosed |
| WO-2005045394-A2 | SILICONE COMPOSITION FOR BIOCOMPATIBLE MEMBRANE | DEXCOM, INC. (US) | 2005-05-19 | — | — | WO | disclosed |
| US-20050090607-A1 | Silicone composition for biocompatible membrane | DEXCOM, INC. (US) | 2005-04-28 | — | — | US | disclosed |
| US-20040159394-A1 | of olefinically unsaturated monomers, including esters of dicarboxy acids, onto polyalkylene oxides containing a resin which improves tackiness and compatibility of the adhesive; use in the labelling of recyclable or reuseable hollow containers | PARALLEL WIRELESS, INC. | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105320-A1 | Biodal Compositions Containing 1,2-Benzisothiazolin-3-One And 1,2-Dibromo-2,4-Dicyanobutane | BRSK1, BRSK2, BRD1 | TSHR 4180/4885MAPK1 132/4885MEN1 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.