⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744066 | 1.00 | — | — | |
| SCHEMBL2449252 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL19939683 | 0.78 | — | — | |
| SCHEMBL9353672 | 0.78 | — | — | |
| SCHEMBL17294351 | 0.76 | — | — | |
| SCHEMBL30322778 | 0.73 | — | — | |
| SCHEMBL24304565 | 0.72 | — | — | |
| SCHEMBL1031550 | 0.70 | — | — | |
| SCHEMBL30508151 | 0.70 | — | — | |
| SCHEMBL25057 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536489-A | Novel compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2017-03-22 | — | — | CN | disclosed |
| EP-2099444-A1 | USE OF D-SERINE DERIVATIVES FOR THE TREATMENT OF ANXIETY DISORDERS | NPS PHARMACEUTICALS, INC. (CA) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008070994-A1 | USE OF D-SERINE DERIVATIVES FOR THE TREATMENT OF ANXIETY DISORDERS | NPS PHARMACEUTICALS, INC. (CA) | 2008-06-19 | — | — | WO | disclosed |