⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769376 | 1.00 | — | — | |
| SCHEMBL9078197 | 0.95 | GABRR1 (0.58) | — | |
| SCHEMBL3156859 | 0.88 | GABRR1 (0.56) | — | |
| SCHEMBL5616287 | 0.88 | GABRR1 (0.56) | — | |
| SCHEMBL285534 | 0.85 | GABRR1 (0.58) | — | |
| SCHEMBL18163464 | 0.85 | GABRR1 (0.58) | — | |
| SCHEMBL26138089 | 0.83 | SLC22A6 (0.75) | — | |
| SCHEMBL21566556 | 0.81 | GPR84 (0.64) | — | |
| SCHEMBL3089526 | 0.80 | SLC22A6 (0.71) | — | |
| SCHEMBL16585355 | 0.80 | GABRR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57063096-A | — | — | None | — | — | JP | disclosed |
| JP-53005113-A | — | — | None | — | — | JP | disclosed |
| JP-1060394-A | — | — | None | — | — | JP | disclosed |
| JP-4091793-A | — | — | None | — | — | JP | disclosed |
| JP-3091477-A | — | — | None | — | — | JP | disclosed |
| CN-105176906-B | L-threonine genetic engineering produces bacterium | SHANGHAI RESEARCH AND DEVELOPMENT CENTER OF INDUSTRIAL BIOTECHNOLOGY (CN) | 2018-08-31 | — | — | CN | disclosed |
| US-9994881-B2 | Functionalized carboxylic acids and alcohols by reverse fatty acid oxidation in engineered microbes | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2753689-B1 | FUNCTIONALIZED CARBOXYLIC ACIDS AND ALCOHOLS BY REVERSE FATTY ACID OXIDATION | UNIV RICE WILLIAM M (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20140273110-A1 | FUNCTIONALIZED CARBOXYLIC ACIDS AND ALCOHOLS BY REVERSE FATTY ACID OXIDATION | WILLIAM MARSH RICE UNIVERSITY (US) | 2014-09-18 | — | — | US | disclosed |
| US-8101386-B2 | Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation | ARCHER DANIELS MIDLAND COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| JP-H0391477-A | YEAST WITH HIGH THREONINE CONTENT | KYOWA HAKKO KOGYO CO LTD | 1991-04-17 | — | — | JP | disclosed |
| JP-S6460394-A | PRODUCTION OF L-THREONINE BY FERMENTATION | MITSUI TOATSU CHEMICALS | 1989-03-07 | — | — | JP | disclosed |
| EP-0271838-A2 | Novel microorganisms capable of assimilating lactose | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0205849-A2 | Process for producing L-Threonine by Fermentation | TORAY INDUSTRIES, INC. (JP) | 1986-12-30 | — | — | EP | disclosed |
| JP-S5763096-A | PRODUCTION OF L-METHIONINE THROUGH FERMENTATION PROCESS | AJINOMOTO CO INC | 1982-04-16 | — | — | JP | disclosed |
| JP-S535113-A | 5-AMINO-3-HYDROXY-VALERIANIC ACID, ITS DERIVATIVES AND IMPROVERS OF SMOKING TASTE FOR TOBACCO CONTAINING THE SAME | JAPAN TOBACCO INC | 1978-01-18 | — | — | JP | disclosed |
| JP-H00391477-A | — | — | 0001-01-01 | — | — | JP | disclosed |
| JP-H00491793-A | — | — | 0001-01-01 | — | — | JP | disclosed |
| JP-S05763096-A | — | — | 0001-01-01 | — | — | JP | disclosed |
| JP-S06460394-A | — | — | 0001-01-01 | — | — | JP | disclosed |