SCHEMBL285534

SCHEMBL285534

NCCCC(O)CC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 3/20 0.58
LMNA P02545 3/20 0.58
GPR84 Q9NQS5 4/20 0.57
SLC22A6 Q4U2R8 1/20 0.55
THRB P10828 2/20 0.44
BLM P54132 2/20 0.44
KMT2A Q03164 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
GABRR3 A8MPY1 1/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
HDAC3 O15379 1/20 0.44
GABBR2 O75899 1/20 0.44
CYP1A2 P05177 1/20 0.44
GABRA1 P14867 1/20 0.44
TSHR P16473 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRR2 P28476 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18163464 1.00 GABRR1 (0.58) GABRR1LMNAGPR84SLC22A6THRB
SCHEMBL21566556 0.91 GPR84 (0.64) GABRR1LMNAGPR84SLC22A6THRB
SCHEMBL382930 0.85
SCHEMBL7769376 0.85
SCHEMBL28922166 0.85 GPR84 (0.67) GABRR1LMNAGPR84SLC22A6MAPT
SCHEMBL966415 0.85 GPR84 (0.74) GABRR1LMNAGPR84SLC22A6MAPT
SCHEMBL285410 0.82 CPB2 (0.41) GABRR1LMNAGPR84SLC22A6THRB
SCHEMBL27804009 0.81 GPR84 (0.57) GABRR1LMNAGPR84SLC22A6MAPT
SCHEMBL9078197 0.81 GABRR1 (0.58) GABRR1LMNAGPR84SLC22A6MAPT
SCHEMBL4744436 0.79 GPR84 (0.61) GABRR1LMNAGPR84SLC22A6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2885400-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS Celexion, LLC (US) 2015-06-24 EP claimed
WO-2014028026-A9 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC (US) 2015-03-26 WO claimed
WO-2014028026-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC (US) 2014-02-20 WO claimed
US-20130017593-A1 Biological Synthesis of Difunctional Hexanes and Pentanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2013-01-17 US claimed
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 US disclosed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 US disclosed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 CN disclosed
US-20240182935-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2024-06-06 US disclosed
US-11834690-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2023-12-05 US disclosed
EP-4273255-A2 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF HEXAMETHYLENEDIAMINE Genomatica, Inc. (US) 2023-11-08 EP disclosed
US-20230287435-A1 MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS AGAIN BIO APS (DK) 2023-09-14 US disclosed
US-20120302562-A1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS, INC. 2012-11-29 US disclosed
US-20120301950-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC 2012-11-29 US disclosed
US-20120301950-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC 2012-11-29 US disclosed
US-20120301950-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC 2012-11-29 US disclosed
US-20120282661-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-11-08 US disclosed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 EP disclosed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 US disclosed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 GABRR1 2326/4885LMNA 2536/4885GPR84 3361/4885
US-12577591-B2 Microorganisms and methods for increasing co-factors ABAT, HADHB, MMAB GABRR1 2959/4885LMNA 1752/4885GPR84 3602/4885
US-20120302562-A1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE NOTUM, CES1, ACHE GABRR1 4249/4885LMNA 2367/4885GPR84 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.