Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DNM1L | O00429 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826390 | 0.91 | MAPT (0.50) | ALDH1A1DNM1LARNPC1RAB9A | |
| SCHEMBL3821644 | 0.90 | LMNA (0.49) | ALDH1A1HSD17B10DNM1LARNPC1 | |
| SCHEMBL3064271 | 0.86 | AR (0.50) | ALDH1A1DNM1LARNPC1RAB9A | |
| SCHEMBL4738762 | 0.86 | AR (0.44) | ALDH1A1DNM1LARNPC1RAB9A | |
| SCHEMBL4734899 | 0.85 | AR (0.42) | ALDH1A1ARNPC1RAB9ALMNA | |
| SCHEMBL4739647 | 0.85 | AR (0.43) | ALDH1A1DNM1LARNPC1RAB9A | |
| SCHEMBL4735442 | 0.84 | AR (0.43) | ALDH1A1ARNPC1RAB9ALMNA | |
| SCHEMBL3059056 | 0.83 | AR (0.47) | ALDH1A1DNM1LARNPC1RAB9A | |
| SCHEMBL3047804 | 0.83 | AR (0.47) | ALDH1A1DNM1LARNPC1RAB9A | |
| SCHEMBL3071134 | 0.82 | AR (0.47) | ALDH1A1ARNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |