Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | DNM1L | O00429 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737963 | 0.89 | MEN1 (0.39) | LMNAMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL4739654 | 0.89 | LMNA (0.38) | NPC1RAB9ALMNAHTTMAPT | |
| SCHEMBL4736789 | 0.89 | AR (0.40) | ARNPC1RAB9ALMNAHTT | |
| SCHEMBL4735442 | 0.88 | AR (0.43) | ARNPC1RAB9ALMNAHTT | |
| SCHEMBL4735240 | 0.88 | KDM4E (0.44) | HTTGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3821644 | 0.87 | LMNA (0.49) | ARNPC1RAB9ALMNAHTT | |
| SCHEMBL4734899 | 0.86 | AR (0.42) | ARNPC1RAB9ALMNAHTT | |
| SCHEMBL4738359 | 0.85 | LMNA (0.41) | NPC1RAB9ALMNAHTTMAPT | |
| SCHEMBL3826390 | 0.85 | MAPT (0.50) | ARNPC1RAB9ALMNAHTT | |
| SCHEMBL3829564 | 0.85 | ALDH1A1 (0.46) | ARNPC1RAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |