Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381926 | 0.86 | ITGB3 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL381927 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL420521 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL381928 | 0.83 | ITGB3 (0.40) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL381721 | 0.82 | ITGB3 (0.40) | MAPTFLT3FLT1KDRAURKA | |
| SCHEMBL383427 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL382606 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL383240 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL382605 | 0.76 | CASR (0.41) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL6499269 | 0.76 | VCP (0.40) | NPSR1MAPTLMNAKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |