Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341365 | 0.87 | P2RX7 (0.52) | P2RX7RIPK1NFKB1NFKB2RELA | |
| SCHEMBL3343887 | 0.87 | P2RX7 (0.52) | P2RX7RIPK1NFKB1NFKB2RELA | |
| SCHEMBL4349642 | 0.84 | P2RX7 (0.53) | P2RX7RIPK1POLB | |
| SCHEMBL26984284 | 0.84 | P2RX7 (0.50) | P2RX7RIPK1NFKB1NFKB2RELA | |
| SCHEMBL4340176 | 0.81 | P2RX7 (0.58) | P2RX7RIPK1 | |
| SCHEMBL6316944 | 0.80 | SMN1; SMN2 (0.51) | P2RX7MAOAMAOBNFKB1NFKB2 | |
| SCHEMBL4174627 | 0.79 | P2RX7 (0.51) | P2RX7RIPK1 | |
| SCHEMBL14115699 | 0.77 | NFKB1 (0.47) | P2RX7NFKB1NFKB2RELA | |
| SCHEMBL3159251 | 0.76 | P2RX7 (0.49) | P2RX7SIGMAR1 | |
| SCHEMBL20449200 | 0.76 | P2RX7 (0.49) | P2RX7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191043-B1 | Separating medium, method for its production and its use | TOSOH CORP (JP) | 2009-08-26 | — | — | EP | disclosed |
| US-6881342-B2 | Optically active poly (N-methylbenzylmaleimide), method for its production and its use | TOSOH CORPORATION (JP) | 2005-04-19 | — | — | US | disclosed |
| US-6712971-B2 | ANIONIC POLYMERIZATION OF (S)-(-)-N-ALPHA-METHYLBENZYL MALEIMIDE IN THE PRESENCE OF AN ASYMMETRIC LIGAND; HIGH SPECIFIC ROTATION AND MOLECULAR WEIGHT | TOSOH CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |
| US-6509478-B2 | Having a specific rotation (( alpha )43525) of at least +30 degrees. | TOSOH CORPORATION (JP) | 2003-01-21 | — | — | US | disclosed |