Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706591 | 0.87 | NPC1 (0.36) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL708779 | 0.87 | NPC1 (0.36) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL11614327 | 0.86 | NPC1 (0.41) | CA2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL3830756 | 0.85 | NPC1 (0.45) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11416629 | 0.85 | NPC1 (0.38) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL13021503 | 0.82 | CA1 (0.43) | CA1CA2NPC1RAB9AALDH1A1 | |
| SCHEMBL11416372 | 0.81 | RORC (0.37) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24205703 | 0.81 | CA1 (0.42) | CA1CA2NPC1RAB9AALDH1A1 | |
| SCHEMBL8922405 | 0.80 | CA1 (0.40) | CA1CA2NPC1RAB9AALDH1A1 | |
| SCHEMBL712970 | 0.79 | CYP3A4 (0.43) | NPC1RAB9AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127586-A | HYDROXYPHENYL BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1978-11-28 | — | — | US | disclosed |