Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830837 | 0.96 | HTT (0.47) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL3834128 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL11050670 | 0.81 | TSHR (0.58) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL20712037 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL16809085 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL18668929 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL14172515 | 0.80 | LMNA (0.49) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL18668858 | 0.80 | LMNA (0.43) | ALDH1A1MAPK1L3MBTL1TSHRLMNA | |
| SCHEMBL4393835 | 0.79 | HTT (0.41) | ALDH1A1TSHRKMT2AMEN1HPGD | |
| SCHEMBL4397152 | 0.79 | HTT (0.41) | ALDH1A1TSHRKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |