Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.49 |
| ▸ | ITGAV | P06756 | 6/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382401 | 0.91 | ITGB3 (0.46) | ITGB3ITGAVITGA2BPRMT5WDR77 | |
| SCHEMBL381720 | 0.88 | ITGB3 (0.43) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL6499257 | 0.87 | PRMT5 (0.38) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382989 | 0.85 | ITGB3 (0.36) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382567 | 0.84 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL383135 | 0.83 | ITGB3 (0.43) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383667 | 0.82 | ITGB3 (0.52) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL381829 | 0.80 | ITGB3 (0.57) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382099 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383138 | 0.79 | ITGB3 (0.43) | ITGB3ITGAVITGA2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |