Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.36 |
| ▸ | ITGAV | P06756 | 7/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382401 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVPRMT5ITGA2BGRIN2B | |
| SCHEMBL383137 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVPRMT5ITGA2BLMNA | |
| SCHEMBL381720 | 0.85 | ITGB3 (0.43) | ITGB3ITGAVPRMT5ITGA2BGRIN2B | |
| SCHEMBL6499257 | 0.83 | PRMT5 (0.38) | ITGB3ITGAVPRMT5ITGA2BGRIN2B | |
| SCHEMBL382907 | 0.82 | GRIN2B (0.35) | ITGB3ITGAVPRMT5GRIN2BL3MBTL1 | |
| SCHEMBL382611 | 0.82 | ITGB3 (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL383201 | 0.79 | ITGB3 (0.40) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382990 | 0.79 | ITGB3 (0.38) | ITGB3ITGAVPRMT5GRIN2BMAPT | |
| SCHEMBL381824 | 0.78 | ITGB3 (0.38) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382988 | 0.77 | PRMT5 (0.38) | ITGB3ITGAVPRMT5GRIN2BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |