SCHEMBL38316

SCHEMBL38316

O=C1C=CC(=O)N1c1ccc(Nc2ccccc2)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
GAA P10253 2/20 0.52
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GLA P06280 1/20 0.52
MAPT P10636 1/20 0.52
RECQL P46063 1/20 0.52
HSP90AA1 P07900 2/20 0.51
PIN1 Q13526 1/20 0.46
TLR9 Q9NR96 2/20 0.46
CDC25B P30305 4/20 0.43
ALDH1A1 P00352 3/20 0.43
ATM Q13315 3/20 0.43
HPGD P15428 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367034 1.00 MEN1 (0.52) MEN1GAAKMT2ATDP1KDM4E
Anthranilamide SCHEMBL1493156 0.84 CDC25B (0.41) MEN1GAAKMT2ATDP1KDM4E
SCHEMBL5077484 0.80 TLR9 (0.68) TDP1HSP90AA1TLR9ALDH1A1ATM
SCHEMBL31180023 0.80 TLR9 (0.68) TDP1HSP90AA1TLR9ALDH1A1ATM
SCHEMBL1087460 0.80 HSP90AA1 (0.58) MEN1GAAKMT2ATDP1KDM4E
SCHEMBL28075355 0.79 MEN1 (0.53) MEN1GAAKMT2ATDP1KDM4E
SCHEMBL11962221 0.76 GAA (0.85) MEN1GAAKMT2ATDP1KDM4E
SCHEMBL3182283 0.75 HSP90AA1 (0.53) MEN1GAAKMT2ATDP1KDM4E
SCHEMBL17073996 0.73 HSP90AA1 (0.46) MEN1GAAKMT2ATDP1KDM4E
SCHEMBL31179969 0.72 TLR9 (0.68) TDP1HSP90AA1TLR9ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3969 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725227-B2 Devices and methods for examining drug effects on microorganisms ESSENLIX CORPORATION (US) 2023-08-15 US claimed
US-20220237930-A1 CELL AGE CLASSIFICATION AND DRUG SCREENING FOUNTAIN THERAPEUTICS INC (US) 2022-07-28 US claimed
US-20210275693-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC. 2021-09-09 US claimed
CN-112689758-A Device and method for examining the effect of a drug on microorganisms ESSENLIX公司 2021-04-20 CN claimed
US-10961571-B2 Polymerase assay with a FRET substrate Life Technologies Corporation (US) 2021-03-30 US claimed
US-20200399675-A1 DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS ESSENLIX CORPORATION (US) 2020-12-24 US claimed
US-10605805-B2 Device and system for analyzing a sample, particularly blood, as well as methods of using the same ESSENLIX CORPORATION (US) 2020-03-31 US claimed
US-10453420-B2 Base film, laminated structure including the same, and display device LG CHEM, LTD. (KR) 2019-10-22 US claimed
US-20190307904-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC (US) 2019-10-10 US claimed
EP-3541960-A2 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS Quest Diagnostics Investments LLC (US) 2019-09-25 EP claimed
CN-104871118-B Basement membrane includes the laminar structure and display device of the basement membrane LG化学株式会社 2017-07-18 CN claimed
EP-3096741-A2 HYBRIDOSOMES, COMPOSITIONS COMPRISING THE SAME, PROCESSES FOR THEIR PRODUCTION AND USES THEREOF Anjarium Biosciences AG (CH) 2016-11-30 EP claimed
CN-105934240-A Hybrid, composition containing the hybrid, preparation method and use thereof 安杰瑞姆生物科学公司 2016-09-07 CN claimed
US-20150299841-A1 BASE FILM, LAMINATED STRUCTURE INCLUDING THE SAME, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2015-10-22 US claimed
CN-104871118-A BASE FILM, AND LAMINATED STRUCTURE AND DISPLAY DEVICE COMPRISING SAME LG CHEMICAL LTD 2015-08-26 CN claimed
WO-2015110957-A2 HYBRIDOSOMES, COMPOSITIONS COMPRISING THE SAME, PROCESSES FOR THEIR PRODUCTION AND USES THEREOF DE BEER JOEL (CH) 2015-07-30 WO claimed
US-8513350-B2 Forming patterned film; radiation transparent, reduced dielectrics, solvent resistance, waterproofing, acid and alkali resistance, heat resistance, adhesives properties to substrate JNC CORPORATION (JP) 2013-08-20 US claimed
US-20090191386-A1 POSITIVE PHOTOSENSITIVE POLYMER COMPOSITION CHISSO CORPORATION (JP) 2009-07-30 US claimed
US-20080207807-A1 POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION CHISSO CORPORATION (JP) 2008-08-28 US claimed
US-4942136-A Method for production of fluorescence-labeled Fab' AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-07-17 US claimed