Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614302 | 0.75 | ERN1 (0.58) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL7286007 | 0.70 | ERN1 (0.56) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL6987350 | 0.68 | MEN1 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL27945949 | 0.66 | ALDH1A1 (0.56) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL17871911 | 0.66 | ALDH1A1 (0.55) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL9558758 | 0.66 | ERN1 (0.50) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL17796053 | 0.66 | MAPT (0.56) | ERN1ALDH1A1MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL31733318 | 0.66 | MEN1 (0.39) | MEN1KMT2AL3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL31733520 | 0.66 | MEN1 (0.39) | ERN1ALDH1A1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL31733582 | 0.66 | MEN1 (0.39) | MEN1KMT2AL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118109-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | disclosed |
| EP-2114947-A1 | INDOLOBENZAZEPINE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | Brystol-Myers Squibb Company (US) | 2009-11-11 | — | — | EP | disclosed |
| EP-2099804-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Brystol-Myers Squibb Company (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008112473-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008097796-A1 | INDOLOBENZAZEPINE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008089027-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-24 | — | — | WO | disclosed |