Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145847 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL10747167 | 0.74 | TSHR (0.40) | TSHRHTT | |
| SCHEMBL6984545 | 0.74 | MEN1 (0.50) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7100629 | 0.72 | SLC6A2 (0.46) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL28402652 | 0.70 | AKR1C3 (0.46) | MEN1KMT2AALDH1A1L3MBTL1HTT | |
| SCHEMBL31070259 | 0.70 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL6980776 | 0.69 | HTT (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7682179 | 0.69 | HTT (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3832033 | 0.68 | ERN1 (0.43) | MEN1KMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3653836 | 0.67 | TAS1R3 (0.37) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |