Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951191 | 0.76 | NNMT (0.53) | NNMTGRM5 | |
| SCHEMBL6425767 | 0.74 | NNMT (0.55) | NNMTGRM5 | |
| SCHEMBL15653050 | 0.73 | MAP4K1 (0.41) | GRM5 | |
| SCHEMBL21605734 | 0.73 | GRM5 (0.50) | GRM5 | |
| SCHEMBL5253609 | 0.73 | MEN1 (0.32) | — | |
| SCHEMBL16823386 | 0.71 | NNMT (0.35) | NNMTGRM5 | |
| SCHEMBL1602453 | 0.71 | KDM4E (0.33) | NNMTGRM5 | |
| SCHEMBL20595712 | 0.71 | HTT (0.34) | NNMTGRM5 | |
| SCHEMBL19908287 | 0.71 | ALDH1A1 (0.35) | NNMTGRM5 | |
| SCHEMBL29712705 | 0.69 | NNMT (0.49) | NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091951-A2 | PYRIDO[2,3-B]PYRAZINE AND[1,8]-NAPHTYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2007130468-A2 | PYRIDO [2, 3-B] PYRAZINE AND [1, 8] -NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2007-11-15 | — | — | WO | claimed |
| EP-2091951-A2 | PYRIDO[2,3-B]PYRAZINE AND[1,8]-NAPHTYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2007130468-A2 | PYRIDO [2, 3-B] PYRAZINE AND [1, 8] -NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2007-11-15 | — | — | WO | disclosed |