Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | UBE2M | P61081 | 16/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 16/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306360 | 0.86 | P2RX3 (0.43) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL1306437 | 0.86 | P2RX3 (0.43) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL1306362 | 0.86 | P2RX3 (0.43) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL3834922 | 0.80 | P2RX3 (0.39) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL3832922 | 0.78 | P2RX3 (0.38) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL1307047 | 0.77 | P2RX3 (0.62) | P2RX3DAPK1PIM3 | |
| SCHEMBL1307045 | 0.77 | P2RX3 (0.62) | P2RX3DAPK1PIM3 | |
| SCHEMBL3834741 | 0.77 | MEN1 (0.38) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL3826815 | 0.77 | TRPM8 (0.38) | P2RX3DAPK1PIM3TSHR | |
| SCHEMBL3832337 | 0.77 | LPAR1 (0.40) | P2RX3DAPK1PIM3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |