Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.46 |
| ▸ | RARB | P10826 | 10/20 | 0.46 |
| ▸ | RARG | P13631 | 10/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381962 | 0.80 | RARA (0.44) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL382577 | 0.79 | RARG (0.67) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL382163 | 0.74 | HRH3 (0.43) | SIRT2SIRT1ALDH1A1MAPTMEN1 | |
| SCHEMBL382759 | 0.73 | RARB (0.57) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL380874 | 0.72 | RARA (0.51) | RARARARBRARGLMNA | |
| SCHEMBL381872 | 0.71 | RARG (0.80) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL381961 | 0.71 | RARG (0.80) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL382160 | 0.71 | RARG (0.81) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL382430 | 0.71 | RARG (0.48) | RARARARBRARGSIRT2SIRT1 | |
| SCHEMBL382839 | 0.70 | RARG (0.44) | RARARARBRARGMAPTSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | disclosed |