Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.44 |
| ▸ | RARB | P10826 | 14/20 | 0.44 |
| ▸ | RARA | P10276 | 13/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382380 | 0.86 | RARB (0.42) | RARGRARBRARAMAOBGAA | |
| SCHEMBL381770 | 0.82 | RARG (0.58) | RARGRARBRARASLC6A9MAPT | |
| SCHEMBL382090 | 0.81 | RARA (0.48) | RARGRARBRARA | |
| SCHEMBL382766 | 0.79 | RARG (0.65) | RARGRARBRARA | |
| SCHEMBL381962 | 0.78 | RARA (0.44) | RARGRARBRARATP53MAPK1 | |
| SCHEMBL3439183 | 0.77 | RARG (0.63) | RARGRARBRARA | |
| SCHEMBL382994 | 0.77 | RARA (0.51) | RARGRARBRARASMN1; SMN2KDM4E | |
| SCHEMBL381882 | 0.74 | RARG (0.66) | RARGRARBRARA | |
| SCHEMBL382244 | 0.73 | RARB (0.56) | RARGRARBRARAMAOBGAA | |
| SCHEMBL383525 | 0.72 | RARG (0.62) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | disclosed |